Recombinant Human IL12P40&P19 Heterodimer Protein (Active)

SKU: BCACP-001146 Category:

Product Specifications

Product SKUBCACP-001146
Product DescriptionRecombinant Human IL12P40&P19 Heterodimer Protein protein is expressed from Mammalian cell with Tag free. It contains 23-328aa(IL12P40)&20-189aa(P19). [Accession | P29460 AAG37232].
Uniprot No.P29460 AAG37232
Gene NamesIL-23
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region23-328aa(IL12P40)&20-189aa(P19)
SpeciesHomo sapiens (Human)
Tag InfoTag free
Molecular weight55.0 kDa (IL-23 single chain); 36.5 kDa (p40) & 18.5 kDa (p19)
ActivityDetermined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 2.0-3.0 ng/ml of Noggin.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesSGRF; IL-23p19; CLMF p40; IL-12 subunit p40; NKSF2

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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