Recombinant Protein Products & Technology Platforms
20,000+ Recombinant Proteins · Six Core Technology Platforms · 80% Eukaryotic Expression
biocrestsci leverages five expression systems – prokaryotic, yeast, insect, mammalian, and cell-free – in combination with six proprietary protein preparation technologies to develop over 20,000 recombinant protein products. All proteins meet rigorous standards, including >90% purity, <1.0 EU/μg endotoxin, and high biological activity. Our portfolio supports a broad range of applications, including drug discovery, diagnostic development, and fundamental research.
I. Core Technology Platforms: Addressing Difficult-to-Express Proteins
1. Virus-Like Particles (VLPs) Platform
Based on virus-like particle technology, this platform enables efficient display of complex antigens and is well-suited for vaccine development and antibody screening.
2. Detergent Micelle Platform
This system utilizes detergent micelles to stabilize transmembrane proteins while preserving their native conformation and functional integrity.
3. Synthetic Nanodisc Platform
Synthetic nanodiscs are employed to mimic the native cell membrane environment, thereby supporting the structural and functional activity of membrane proteins, including GPCRs.
4. Exosome (EXO) Platform
This exosome-based platform produces highly biocompatible protein complexes and facilitates research on intercellular communication.
5. Membrane Nanoparticle (MNP) Platform
Membrane nanoparticle technology enables soluble expression and efficient purification of functional membrane proteins.
6. Cell-Free Expression System
This system circumvents cell-associated toxicity limitations and enables rapid synthesis of difficult-to-express proteins within 2–3 days.
II. Product Overview: Quantity and Quality Assured
Key Performance Indicators
20,000+ recombinant protein offerings
80% expressed in eukaryotic systems
- 90% purity, as verified by SDS-PAGE and HPLC
<1.0 EU/μg endotoxin, determined by the LAL method
Supported Application Areas
CAR-T cell therapy · Antibody-drug conjugates (ADCs) · Immuno-oncology · Organoid culture · Vaccine development · In vitro diagnostic development
Quality Commitment
Each protein lot undergoes rigorous quality control, including assessments of concentration, purity, endotoxin levels, biological activity, and sequence integrity. If a product fails to meet the specifications stated in the technical datasheet, we provide comprehensive technical support, product replacement, or a full refund.
III. Protein Classification
By Protein Type
Cytokines and growth factors
Transmembrane proteins and GPCRs
Kinases and other enzymes
Hormones and peptides
Viral proteins
Native proteins and recombinant antigens
All products can be filtered by target, species, tag, and expression system.
IV. Custom Services: From Gene Synthesis to Gram-Scale Production
When standard catalog products do not meet specific research or development needs, biocrestsci offers flexible and rapid custom protein services.
Service Scope
Gene synthesis and codon optimization
Expression vector construction (tagged or tag-free)
Access to all six technology platforms
Choice of expression systems: prokaryotic, yeast, insect, mammalian, or cell-free
Purification and quality control: >90% purity and <1.0 EU/μg endotoxin as standard; higher specifications are available upon request
Production scale: from micrograms to grams (mg to g)
Turnaround Times
Routine proteins: 2–4 weeks
Transmembrane and difficult-to-express proteins: 4–8 weeks
Cell-free system: 2–3 days
Case Examples
Production of a high-activity, full-length Claudin-18.2 transmembrane protein using the Synthetic Nanodisc Platform
Development of an RSV F protein with a 3-fold increase in immunogenicity using the VLPs Platform
Synthesis of the cytotoxic pyroptosis-associated protein GSDMD within 3 days using the Cell-Free Expression System
V. Service Guarantees and Key Advantages
100% Quality Guarantee: Unconditional replacement or full refund if product performance does not match the datasheet specifications
Extensive Portfolio: Over 20,000 products covering the majority of high-demand targets
Flexible Formats: Available in liquid or lyophilized form, in sizes of 20 μg, 100 μg, 1 mg, and custom bulk quantities
Expert Scientific Support: PhD-level team providing technical guidance on protein selection and experimental applications
VI. Access Products and Services
Inquire within the recombinant protein database
Submit a custom service request
Download technical resources, including datasheets and application notes